Haematopoietic progenitor and stem cells can be identified among bone marrow cells and circulating white blood cells. Another interesting source of progenitor cells is cord blood. Aggressive novel strategies for therapy of malignant diseases require the isolation and storage of these cells. The infusion of concentrates of progenitor and stem cells following high-dose chemo- and radiotherapy enables the reconstitution of haematopoiesis.
A major focus of research is the isolation of haematopoietic progenitor cells in children. Main research interests are the adaptation of apheresis procedures to clinical problems of the isolation of progenitor cells in paediatric patients with small total blood volume and flow cytometry as method of quality control and improvement. In the recently opened cord blood bank, research is focused to cord blood derived-hematopoietic progenitor cells in cooperation with the departments of pediatrics, gynecology and obstetrics and other departments of the hospital.